Which pancreatic hormone lowers blood sugar?

• A. Insulin
• B. Glucagon
• C. Somatostatin
• D. Amylin

Answer: (A)

Insulin lowers blood glucose by promoting uptake of glucose into cells and storage of glucose as glycogen. It’s secreted by the pancreatic beta cells in response to high blood sugar after a meal. Insulin moves glucose into muscle and fat cells by increasing GLUT4 transporters on the cell surface and signals the liver to store glucose as glycogen, while also supporting other storage processes like fat and protein synthesis. By contrast, glucagon raises blood glucose, somatostatin inhibits the release of insulin and glucagon, and amylin mainly slows gastric emptying and helps regulate postprandial glucose. So the hormone that lowers blood sugar is insulin.