Which cells secrete the inactive enzyme pepsinogen in the stomach?

Enhance your knowledge of the digestive system with our quiz. Answer multiple choice questions with detailed explanations. Prepare effectively for your anatomy and physiology exam!

Multiple Choice

Which cells secrete the inactive enzyme pepsinogen in the stomach?

Explanation:
Pepsinogen, the inactive precursor of the enzyme pepsin, is produced and secreted by the gastric glands’ chief cells. These cells reside in the stomach lining and release pepsinogen into the stomach lumen. The acidic environment created by hydrogen chloride (HCl) from parietal cells cleaves pepsinogen into active pepsin, which then begins protein digestion. Parietal cells are responsible for secreting HCl and intrinsic factor, not pepsinogen. Goblet cells secrete mucus to shield the stomach lining. Salivary amylase comes from the salivary glands and functions in the mouth, not in the stomach.

Pepsinogen, the inactive precursor of the enzyme pepsin, is produced and secreted by the gastric glands’ chief cells. These cells reside in the stomach lining and release pepsinogen into the stomach lumen. The acidic environment created by hydrogen chloride (HCl) from parietal cells cleaves pepsinogen into active pepsin, which then begins protein digestion.

Parietal cells are responsible for secreting HCl and intrinsic factor, not pepsinogen. Goblet cells secrete mucus to shield the stomach lining. Salivary amylase comes from the salivary glands and functions in the mouth, not in the stomach.

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