Which cells secrete pepsinogen in the stomach?

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Enhance your knowledge of the digestive system with our quiz. Answer multiple choice questions with detailed explanations. Prepare effectively for your anatomy and physiology exam!

Multiple Choice

Which cells secrete pepsinogen in the stomach?

Explanation:
The main idea is which stomach cells make the pepsinogen precursor. Pepsinogen is produced by gastric chief cells in the gastric glands of the stomach. It is released as an inactive enzyme and then, in the acidic environment created mainly by HCl from parietal cells, it is converted into active pepsin to begin protein digestion. Parietal cells supply the acid, and G cells along with enteroendocrine cells secrete hormones like gastrin, but they do not secrete pepsinogen. So the cells that secrete pepsinogen are the chief cells.

The main idea is which stomach cells make the pepsinogen precursor. Pepsinogen is produced by gastric chief cells in the gastric glands of the stomach. It is released as an inactive enzyme and then, in the acidic environment created mainly by HCl from parietal cells, it is converted into active pepsin to begin protein digestion. Parietal cells supply the acid, and G cells along with enteroendocrine cells secrete hormones like gastrin, but they do not secrete pepsinogen. So the cells that secrete pepsinogen are the chief cells.

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