Which cells secrete pepsinogen and how is it activated?

Unlock all questions

This demo includes only 20 questions. Upgrade to access hundreds of questions, flashcards, exam simulations, and disable ads.

Full question bankExam simulationsFlashcards
From $24.99Unlock all

Enhance your knowledge of the digestive system with our quiz. Answer multiple choice questions with detailed explanations. Prepare effectively for your anatomy and physiology exam!

Multiple Choice

Which cells secrete pepsinogen and how is it activated?

Explanation:
Pepsinogen is a zymogen released by the stomach’s chief cells into the gastric lumen, and it is activated to the protease pepsin by the acidic environment created by hydrochloric acid from parietal cells. The low pH cleaves pepsinogen to pepsin, which then digests proteins in the stomach (with pepsin can even assist further activation in the acidic setting). Bicarbonate, bile, or other secretions don’t activate pepsinogen, and G cells secrete gastrin (which stimulates acid) rather than pepsinogen. This makes the description that chief cells secrete pepsinogen and it is activated by stomach acid the correct one.

Pepsinogen is a zymogen released by the stomach’s chief cells into the gastric lumen, and it is activated to the protease pepsin by the acidic environment created by hydrochloric acid from parietal cells. The low pH cleaves pepsinogen to pepsin, which then digests proteins in the stomach (with pepsin can even assist further activation in the acidic setting). Bicarbonate, bile, or other secretions don’t activate pepsinogen, and G cells secrete gastrin (which stimulates acid) rather than pepsinogen. This makes the description that chief cells secrete pepsinogen and it is activated by stomach acid the correct one.

More Multiple Choice Questions
Subscribe

Get the latest from Examzify

You can unsubscribe at any time. Read our privacy policy